Alice Gardani
Ankle Range of Motion asymmetry and motor functional tests: A Retrospective Analysis of 24 Months in Ambulant Boys with Duchenne Muscular Dystrophy (DMD)
Autori
- ALICE GARDANI (DEPARTMENT OF CHILD NEUROLOGY AND PSYCHIATRY, IRCCS C. MONDINO FOUNDATION, PAVIA, ITALY – NEURODEVELOPMENTAL THERAPIST TNPEE)
- VALERIA VACCHINI (DEPARTMENT OF CHILD NEUROLOGY AND PSYCHIATRY, IRCCS C. MONDINO FOUNDATION, PAVIA, ITALY – NEURODEVELOPMENTAL THERAPIST TNPEE)
- MARIA IRENE DAINESI (DEPARTMENT OF BRAIN AND BEHAVIORAL SCIENCES, UNIVERSITY OF PAVIA, PAVIA , ITALY – RESIDENT IN NPI)
- ARIANNA IOSCA (DEPARTMENT OF BRAIN AND BEHAVIORAL SCIENCES, UNIVERSITY OF PAVIA, PAVIA , ITALY – RESIDENT IN NPI)
- SARA FUSCO (DEPARTMENT OF BRAIN AND BEHAVIORAL SCIENCES, UNIVERSITY OF PAVIA, PAVIA , ITALY – RESIDENT IN NPI)
- STEFANO PARRAVICINI (DEPARTMENT OF CHILD NEUROLOGY AND PSYCHIATRY, IRCCS C. MONDINO FOUNDATION, PAVIA, ITALY – NPI)
- ANGELA LUCIA BERARDINELLI (DEPARTMENT OF CHILD NEUROLOGY AND PSYCHIATRY, IRCCS C. MONDINO FOUNDATION, PAVIA, ITALY – NPI)
Presentatore
ALICE GARDANI (DEPARTMENT OF CHILD NEUROLOGY AND PSYCHIATRY, IRCCS C. MONDINO FOUNDATION, PAVIA, ITALY)
Modalità
Poster Session
Abstract
“DMD is an X-linked inherited disorder, characterised by progressive weakness leading to severe motor disability and cardiorespiratory involvement that causes premature death.
Historically symmetric behavior of the lower limbs in DMD was assumed for simplicity in data collection and analysis. However, recent studies have challenged this assumption, suggesting that children with DMD may exhibit an asymmetric gait pattern (Vandekerckhove I., et al., 2022; Xiong et al. 2023).
Our retrospective study investigates the presence of ankle ROM asymmetry in patients with DMD and whether it is a factor that may influence patients’ motor function in a sample of 28 DMD subjects over a period of 24 months.
Up 40% of patients showed the presence of ankle ROM asymmetry, confirming that it may be a frequent feature in this population.
In addition, ankle ROM asymmetry was shown to have a statistically significant effect on performance on the 6MWT, with an increased risk of impaired motor performance.
Finally, our study showed that among rehabilitation treatments, the regular use of night splints is a practice that improves motor performance over time. In fact, those who used night splints continuously had a lower risk of poor motor performance, in particular on the 6MWT, but also in the TFT and NSAA.
Further evidences in larger cohort are needed in order to provide evidence-based rehabilitation guidelines.”